1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE

1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE - Names and Identifiers

Name	PP3
Synonyms	PP3 4-AMINO-7-PHENYLPYRAZOL[3,4-D]PYRIMIDINE 4-AMINO-1-PHENYLPYRAZOLE[3,4-D]PYRIMIDINE 4-AMINO-1-PHENYLPYRAZOLO[3,4-D]PYRIMIDINE 4-Amino-1-phenylpyrazolo[3,4-d]pyrimidine 1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE 1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine
CAS	5334-30-5
InChI	InChI=1/C11H9N5/c12-10-9-6-15-16(11(9)14-7-13-10)8-4-2-1-3-5-8/h1-7H,(H2,12,13,14)

1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE - Physico-chemical Properties

Molecular Formula	C11H9N5
Molar Mass	211.22
Density	1.44g/cm³
Melting Point	214-217 °C
Boling Point	364°C at 760 mmHg
Flash Point	173.9°C
Solubility	DMF, DMSO, Hot methanol
Vapor Presure	1.74E-05mmHg at 25°C
Appearance	Off-white solid
Color	Whit to Off-White
Maximum wavelength(λmax)	240nm(H2O (pH 1))(lit.)
BRN	198460
Storage Condition	-20°C
Refractive Index	1.77
MDL	MFCD00022901

1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE - Risk and Safety

Risk Codes	R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed
Safety Description	S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code	29335995
Hazard Note	Irritant

1-PHENYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE - Introduction

PP3(PP3) is an organic compound with the formula C13H11N5. The following is a description of the nature, use, preparation and safety information of PP3:

Nature:
1. Appearance: PP3 is white or light yellow solid.
2. Solubility: PP3 is soluble in some organic solvents, such as dimethyl sulfoxide (DMSO) and methyl carbamate (DMF).
3. Melting Point: The melting point of PP3 is about 160-162 degrees Celsius.

Use:
1. PP3 is a common organic synthesis intermediate, widely used in the synthesis of other compounds. It has an important application in the field of medicine, can be used as the skeleton of drug molecules or as a surface modifier of drug molecules.

Preparation Method:
The preparation method of PP3 is relatively complicated. A common synthesis method is obtained by the condensation reaction of aniline and 2,4-dinitropyrazole [3,4-d] pyrimidine. Specific synthetic steps and conditions can be carried out according to specific experimental protocols.

Safety Information:
1. PP3 has limited toxicity and hazards, but appropriate laboratory procedures and safety measures are still required. Wear appropriate personal protective equipment such as gloves, goggles and lab coats when handling.
2. avoid inhalation of PP3 dust or contact with skin. If the skin or eyes are touched, rinse immediately with plenty of water and seek medical help.
3. During storage and handling, avoid contact with chemicals such as oxidants to prevent fire or explosion.
4. use and storage of PP3, should comply with the relevant safety procedures and regulations.

Last Update：2024-04-09 15:17:58